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http://hdl.handle.net/11690/1902
Authors: | Rosa, Regis Goulart Robinson, Caroline Cabral Veiga, Viviane Cordeiro Cavalcanti, Alexandre Biasi Azevedo, Luciano César Pontes de Machado, Flávia Ribeiro Berwanger, Otavio Avezum, Álvaro Lopes, Renato Delascio Lisboa, Thiago Teixeira, Cassiano Zampieri, Fernando Godinho Tomazini, Bruno Martins Kawano-Dourado, Letícia Schneider, Daniel Souza, Denise de Santos, Rosa da Rosa Minho dos Silva, Sabrina Souza da Trott, Geraldine Gimenes, Bruna dos Passos Souza, Ana Paula de Barroso, Bruna Machado Costa, Lauren Sezerá Brognoli, Liége Gregoletto Pelliccioli, Melissa Pezzetti Studier, Nicole dos Santos Schardosim, Raíne Fogliati de Carli Haubert, Tainá Aparecida Pallaoro, Victoria Emanuele Lobo Oliveira, Debora Mariani de Velho, Pedro Isaacsson Medeiros, Gregory Saraiva Gazzana, Marcelo Basso Zavascki, Alexandre Prehn Pitrez, Paulo Márcio Oliveira, Roselaine Pinheiro de Polanczyk, Carisi Anne Nasi, Luiz Antônio Hammes, Luciano Serpa Falavigna, Maicon |
Title: | Quality of life and long-term outcomes after hospitalization for COVID-19: Protocol for a prospective cohort study (Coalition VII) |
Keywords: | COVID-19;SARS-CoV-2;Quality of life;Patient-reported outcome measures |
Issue Date: | 2021 |
Publisher: | Associação de Medicina Intensiva Brasileira |
Citation: | ROSA, R. G. et al. Quality of life and long-term outcomes after hospitalization for COVID-19: Protocol for a prospective cohort study (Coalition VII). RBTI, v. 33, n. 1, p. 31-37, jan./mar., 2021. Disponível em: https://www.scielo.br/j/rbti/a/4PPZnCTrD4f7FyWFnzDn3kR/?lang=en. Acesso em: 30 jul. 2021. |
Abstract: | Introduction: The long-term effects caused by COVID-19 are unknown. The present study aims to assess factors associated with health-related quality of life and long-term outcomes among survivors of hospitalization for COVID-19 in Brazil. Methods: This is a multicenter prospective cohort study nested in five randomized clinical trials designed to assess the effects of specific COVID-19 treatments in over 50 centers in Brazil. Adult survivors of hospitalization due to proven or suspected SARS-CoV-2 infection will be followed-up for a period of 1 year by means of structured telephone interviews. The primary outcome is the 1-year utility score of health-related quality of life assessed by the EuroQol-5D3L. Secondary outcomes include all-cause mortality, major cardiovascular events, rehospitalizations, return to work or study, physical functional status assessed by the Lawton-Brody Instrumental Activities of Daily Living, dyspnea assessed by the modified Medical Research Council dyspnea scale, need for long-term ventilatory support, symptoms of anxiety and depression assessed by the Hospital Anxiety and Depression Scale, symptoms of posttraumatic stress disorder assessed by the Impact of Event Scale-Revised, and self-rated health assessed by the EuroQol-5D3L Visual Analog Scale. Generalized estimated equations will be performed to test the association between five sets of variables (1- demographic characteristics, 2- premorbid state of health, 3- characteristics of acute illness, 4- specific COVID-19 treatments received, and 5- time-updated postdischarge variables) and outcomes. Ethics and dissemination: The study protocol was approved by the Research Ethics Committee of all participant institutions. The results will be disseminated through conferences and peer-reviewed journals. |
Appears in Collections: | Artigo de Periódico (PPGSDH) |
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File | Description | Size | Format | |
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Quality of life and long-term_RBTI.pdf | Open Access | 162.6 kB | Adobe PDF | View/Open |
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