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Authors: Rosa, Regis Goulart
Robinson, Caroline Cabral
Veiga, Viviane Cordeiro
Cavalcanti, Alexandre Biasi
Azevedo, Luciano César Pontes de
Machado, Flávia Ribeiro
Berwanger, Otavio
Avezum, Álvaro
Lopes, Renato Delascio
Lisboa, Thiago
Teixeira, Cassiano
Zampieri, Fernando Godinho
Tomazini, Bruno Martins
Kawano-Dourado, Letícia
Schneider, Daniel
Souza, Denise de
Santos, Rosa da Rosa Minho dos
Silva, Sabrina Souza da
Trott, Geraldine
Gimenes, Bruna dos Passos
Souza, Ana Paula de
Barroso, Bruna Machado
Costa, Lauren Sezerá
Brognoli, Liége Gregoletto
Pelliccioli, Melissa Pezzetti
Studier, Nicole dos Santos
Schardosim, Raíne Fogliati de Carli
Haubert, Tainá Aparecida
Pallaoro, Victoria Emanuele Lobo
Oliveira, Debora Mariani de
Velho, Pedro Isaacsson
Medeiros, Gregory Saraiva
Gazzana, Marcelo Basso
Zavascki, Alexandre Prehn
Pitrez, Paulo Márcio
Oliveira, Roselaine Pinheiro de
Polanczyk, Carisi Anne
Nasi, Luiz Antônio
Hammes, Luciano Serpa
Falavigna, Maicon
Title: Quality of life and long-term outcomes after hospitalization for COVID-19: Protocol for a prospective cohort study (Coalition VII)
Keywords: COVID-19;SARS-CoV-2;Quality of life;Patient-reported outcome measures
Issue Date: 2021
Publisher: Associação de Medicina Intensiva Brasileira
Citation: ROSA, R. G. et al. Quality of life and long-term outcomes after hospitalization for COVID-19: Protocol for a prospective cohort study (Coalition VII). RBTI, v. 33, n. 1, p. 31-37, jan./mar., 2021. Disponível em: Acesso em: 30 jul. 2021.
Abstract: Introduction: The long-term effects caused by COVID-19 are unknown. The present study aims to assess factors associated with health-related quality of life and long-term outcomes among survivors of hospitalization for COVID-19 in Brazil. Methods: This is a multicenter prospective cohort study nested in five randomized clinical trials designed to assess the effects of specific COVID-19 treatments in over 50 centers in Brazil. Adult survivors of hospitalization due to proven or suspected SARS-CoV-2 infection will be followed-up for a period of 1 year by means of structured telephone interviews. The primary outcome is the 1-year utility score of health-related quality of life assessed by the EuroQol-5D3L. Secondary outcomes include all-cause mortality, major cardiovascular events, rehospitalizations, return to work or study, physical functional status assessed by the Lawton-Brody Instrumental Activities of Daily Living, dyspnea assessed by the modified Medical Research Council dyspnea scale, need for long-term ventilatory support, symptoms of anxiety and depression assessed by the Hospital Anxiety and Depression Scale, symptoms of posttraumatic stress disorder assessed by the Impact of Event Scale-Revised, and self-rated health assessed by the EuroQol-5D3L Visual Analog Scale. Generalized estimated equations will be performed to test the association between five sets of variables (1- demographic characteristics, 2- premorbid state of health, 3- characteristics of acute illness, 4- specific COVID-19 treatments received, and 5- time-updated postdischarge variables) and outcomes. Ethics and dissemination: The study protocol was approved by the Research Ethics Committee of all participant institutions. The results will be disseminated through conferences and peer-reviewed journals.
Appears in Collections:Artigo de Periódico (PPGSDH)

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