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dc.contributor.authorMachado, Flávia R.-
dc.contributor.authorCavalcanti, Alexandre B.-
dc.contributor.authorBraga, Maria A.-
dc.contributor.authorTallo, Fernando S.-
dc.contributor.authorBossa, Aline-
dc.contributor.authorSouza, Juliana L.-
dc.contributor.authorFerreira, Josiane F.-
dc.contributor.authorPizzol, Felipe dal-
dc.contributor.authorMonteiro, Mariana B.-
dc.contributor.authorAngus, Derek C.-
dc.contributor.authorLisboa, Thiago-
dc.contributor.authorAzevedo, Luciano C. P.-
dc.date.accessioned2023-11-20T17:04:12Z-
dc.date.available2023-11-20T17:04:12Z-
dc.date.issued2023-
dc.identifier.citationLISBOA, T. C. et al. Sepsis in Brazilian emergency departments: a prospective multicenter observational study. Internal and Emergency Medicine, v. 18, p. 409-421, 2023. Disponível em: https://link.springer.com/article/10.1007/s11739-022-03179-3. Acesso em: 17 nov. 2023.pt_BR
dc.identifier.urihttp://hdl.handle.net/11690/3739-
dc.description.abstractWe aimed to assess the prevalence, patient allocation adequacy, and mortality of adults with sepsis in Brazilian emergency departments (ED) in a point-prevalence 3-day investigation of patients with sepsis who presented to the ED and those who remained there due to inadequate allocation. Allocation was considered adequate if the patient was transferred to the intensive care unit (ICU), ward, or remained in the ED without ICU admission requests. Prevalence was estimated using the total ED visit number. Prognostic factors were assessed with logistic regression. Of 33,902 ED visits in 74 institutions, 183 were acute admissions (prevalence: 5.4 sepsis per 1000 visits [95% confdence interval (CI): 4.6–6.2)], and 148 were already in the ED; totaling 331 patients. Hospital mortality was 32% (103/322, 95% CI 23.0–51.0). Age (odds ratio (OR) 1.22 [95% CI 1.10–1.37]), Sequential Organ Failure Assessment (SOFA) score (OR 1.41 [95% CI 1.28–1.57]), healthcare-associated infections (OR 2.59 [95% CI 1.24–5.50]) and low-resource institution admission (OR 2.65 [95% CI 1.07–6.90]) were associated with higher mortality. Accredited institutions (OR 0.42 [95% CI 0.21–0.86]) had lower mortality rates. Allocation within 24 h was adequate in only 52.8% of patients (public hospitals: 42.4% (81/190) vs. private institutions: 67.4% (89/132, p<0.001) with 39.2% (74/189) of public hospital patients remaining in the ED until discharge, of whom 55.4% (41/74) died. Sepsis exerts high burden and mortality in Brazilian EDs with frequent inadequate allocation. Modifable factors, such as resources and quality of care, are associated with reduced mortality.pt_BR
dc.language.isoen_USpt_BR
dc.publisherSpringerpt_BR
dc.rightsOpen Accessen_US
dc.subjectSepsispt_BR
dc.subjectLow- and middle-income countriespt_BR
dc.subjectMortalitypt_BR
dc.subjectEmergency departmentpt_BR
dc.titleSepsis in Brazilian emergency departments: a prospective multicenter observational studypt_BR
dc.typeArtigo de periódicopt_BR
Aparece nas coleções:Artigo de Periódico (Educação Física)

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